We consider the drifting p-Laplace operator
\begin{equation*}\Delta_{p,v}u=e^{-v} \text{div}\,(e^v |\nabla u|^{p-2}\nabla u)\end{equation*}
and discuss generalized weighted Hardy-type inequalities associated with the measure
$d\mu=e^{v(x)}dx$. As an application, we obtain several Liouville-type results for positive solutions of the non-linear elliptic problem with singular lower order term
\begin{equation*}-\Delta_{p,v} u\ge c(x) u^{p-1}+B \frac{|\nabla u|^p}{u} \quad \text{in}\ \Omega,\end{equation*}
where Ω is a bounded or an unbounded exterior domain in
${\mathbb{R}}^N$,
$N \gt p \gt 1$,
$B+p-1 \gt 0$, as well as of the non-autonomous quasilinear elliptic problem
\begin{equation*}-\Delta_{p,v} u+b(x)|\nabla u|^{p-1} \ge c(x) u^{p-1}\quad \text{in}\ \Omega,\end{equation*}
with general weights
$b\ge0$ and c > 0. Liouville-type results are also discussed for a class of higher order differential equations.