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Clinical guidelines for personality disorder emphasise the importance of patients being supported to develop psychological skills to help them manage their symptoms and behaviours. But where these mechanisms fail, and hospital admission occurs, little is known about how episodes of acutely disturbed behaviour are managed.
Aims
To explore the clinical characteristics and management of episodes of acutely disturbed behaviour requiring medication in in-patients with a diagnosis of personality disorder.
Method
Analysis of clinical audit data collected in 2024 by the Prescribing Observatory for Mental Health, as part of a quality improvement programme addressing the pharmacological management of acutely disturbed behaviour. Data were collected from clinical records using a bespoke proforma.
Results
Sixty-two mental health Trusts submitted data on 951 episodes of acutely disturbed behaviour involving patients with a personality disorder, with this being the sole psychiatric diagnosis in 471 (50%). Of the total, 782 (82%) episodes occurred in female patients. Compared with males, episodes in females were three times more likely to involve self-harming behaviour or be considered to pose such a risk (22% and 70% respectively: p < 0.001). Parenteral medication (rapid tranquillisation) was administered twice as often in episodes involving females than in males (64 and 34% respectively: p < 0.001).
Conclusions
Our findings suggest that there are a large number of episodes of acutely disturbed behaviour on psychiatric wards in women with a diagnosis of personality disorder. These episodes are characterised by self-harm and regularly prompt the administration of rapid tranquillisation. This has potential implications for service design, staff training, and research.
The contemporary personality disorder approaches found in the Alternative DSM-5 Model and the International Classification of Diseases 11th Edition model of personality disorder are organized along a core axis of personality functioning impairment. Both models represent personality disorder impairment dimensionally. Moreover, the psychological and psychiatric constructs subsumed in this core impairment dimension of personality functioning dovetail with contemporary advances in psychodynamic thinking. Specifically, object relations, attachment/mentalization, intersubjective, and narrative theories are embodied in the personality disorder impairment dimension. This chapter explicates the rich conceptual pluralism of these personality disorder models and identifies implications for measurement, empirical study, and clinical practice.
There are no such things as “personality disorders” distinct from other mental disorders. Distinct personality disorders cannot be identified based on their developmental course or their symptoms. The new ICD and DSM concept of personality disorder as self and interpersonal dysfunction identifies important forms of psychopathology but is not more (or less) related to personality than are other disorders. Rather, personality traits contribute to risk for all forms of mental disorder, and most symptom dimensions are coextensive with dimensions of normal personality, such that persistent symptoms of psychopathology are typically extreme or maladaptive variants of normal personality traits. However, symptoms are merely indicators of risk rather than necessary and sufficient indicators of psychopathology. We draw on our cybernetic dysfunction theory of psychopathology to clarify the role of personality in mental disorder. Psychopathology is defined as “persistent failure to move toward one’s goals, due to failure to generate effective new goals, interpretations, or strategies when existing ones prove unsuccessful.” Personality is exhaustively described by personality traits and characteristic adaptations, the latter being relatively stable goals, interpretations, and strategies that are specified relative to an individual’s particular life circumstances. Psychopathology always involves failure of characteristic adaptations and thus breakdown in personality functioning.
This chapter describes the value of using Contemporary Integrative Interpersonal Theory (CIIT) to understand the self and social impairments that define personality disorders as a group. CIIT’s major tenets are summarized, with a particular emphasis on elaborating how the self and self-functioning are an integral part of interpersonal experience and expression. A generic definition of adaptive interpersonal functioning is provided along with a demonstration of how CIIT can accommodate specific constructs and diagnoses using borderline personality disorder and narcissism as examples.
This chapter brings to light the salience of psychopathy and personality disorders to cult leaders and their followers. Cult leaders present with distinctive personalities that enable them to exert inordinate influence over others and to exhibit highly manipulative and remarkably destructive conduct. Within the literature on cults, narcissistic and antisocial personality disorders are among the most commonly identified character pathologies ascribed to cult leaders. However, psychopathy may be the most fitting yet least explored constellation of traits and behaviors observed in such individuals. This chapter sheds light on the neglected perspective of psychopathic cult leaders while also focusing on the Cluster B personality disorders. The corresponding psychological profile that emerges for cult followers is typified by a noteworthy comorbidity of antisocial, obsessive compulsive, and dependent personality disorders. Suggestive forensic instruments to utilize for the clinical and forensic assessment of cult leaders and their followers include the PCL-R, Rorschach, MMPI-2, and TRAP-18.
CJ experienced mental health problems and trauma during childhood and adolescence. This was treated effectively with psychotherapy. He remembers being exuberant and outgoing. Then, at the age of twenty-one, he developed a severe depressive episode, feeling numb and emotionless, unable to taste anything. Due to the previous history, a diagnosis of personality disorder was suggested, resulting in a delay in starting ECT whilst an inpatient. Relapses followed, the first one in Brazil, where he was quickly offered ECT. Back in the UK, CJ found pervasive barriers to getting treated with ECT, especially maintenance ECT, which he asked for several times, having seen the effect of the acute courses. He had to first try various drug treatments. There was also hesitancy in receiving psychotherapy because it was felt that ECT may affect his ability to engage in therapy. CJ feels that the community team had been inadequately resourced, equipped and educated about ECT to properly support him as an outpatient. CJ finishes the story with a description of his ‘life on maintenance’, which did not stop him from starting studies on a degree and working part-time as a research assistant.
Antisocial personality disorder (ASPD) is a mental condition in which a person exhibits a pattern of repeated disregard for and violation of others’ rights. The Diagnostic and Statistical Manual of Mental Disorders (DSM) provides the framework for diagnosing ASPD. The prevalence rate of ASPD is high in prisons. Genetics, epigenetics, neuroscience, sociology, epidemiology, psychology, and other behavioral science fields have attempted to find a primary etiology. Despite decades of research, the precise etiology of ASPD has not been found, and its pathophysiology remains a complex question. The interaction between genes and the environment appears to be a significant factor in the development of ASPD. Brain imaging in subjects with ASPD has revealed structural brain changes in those with ASPD. Individuals with ASPD are challenging to manage for health care providers because of their complicated clinical presentation, high comorbidity of medical and mental disorders, lack of licensed pharmacotherapies for ASPD, and increased utilization of healthcare resources. ASPD requires tremendous effort from treating clinicians. Clinicians can successfully manage individuals with ASPD if they remain aware of the unique challenges of these patients while thoughtfully applying available research.
Patients with personality disorder, especially borderline personality disorder, are challenging for psychotherapy. Yet there is good evidence that most patients can recover if offered specific forms of specialized therapy that are empirically supported treatments. The majority of research studies in personality disorder have focused on borderline personality disorder, and we have only limited data on other categories. The strongest findings for the efficacy of treatment concern dialectical behavior therapy, but other options may yield similar results. Credible components include teaching emotion regulation skills and a present-oriented focus. Some of the effects of effective therapy could be specific to underlying theory and methods, while others may depend on common factors. A sidebar discusses self-injurious thoughts and behaviors in youth.
Cognitive–behavioural therapy (CBT) has been widely used for a broad range of mental health problems for several decades and has been researched extensively. Its techniques are relatively easy to learn and follow in treatment protocols. Many new CBT-based psychotherapies have been developed that go further than traditional CBT, some specifically addressing personality disorders. These so-called third-wave approaches target emotional responses to situations by using strategies such as mindfulness exercises and acceptance of unpleasant thoughts and feelings (observing thoughts as ‘from afar’). In this article, we discuss the historical context of these therapies, dissect common and specific factors in some treatment modalities often used to treat personality disorders, and suggest potential future directions for research and treatment.
Reflection on diagnoses, treatments and comorbidities – anxiety, obsessive-compulsive disorder and substance misuse or addiction. Stigma, and self-stigmatisation are common, and hard to address. The treatments for bipolar disorder can be difficult to tolerate, including weight gain and sedation. Life as a patient informs work as a psychiatrist as a psychiatrist, hopefully for the good. I do have long periods of being on the high side of normal, which is enjoyable, but can end in disaster. The future with bipolar disorder is ultimately unpredictable.
Borderline personality disorder is a complex mental health condition. Those with the condition have unstable moods, a history of difficulty functioning in relationships, and a dysfunctional self-image. Patients have emotional dysregulation that can lead to impulsive behaviors, self-harm, and fear of abandonment and have significant challenges in life that can lead to poor psychosocial outcomes. Interpersonal relationships can often be intense and dysfunctional and demonstrate frequent conflicts. Emotional dysregulation can lead to rapid and intense mood swings. Impulsivity can lead to issues such as reckless spending, risky sexual behaviors, and substance abuse. The treatment of borderline personality disorder is largely through long-term psychological therapy and the gold standard therapy approach is dialectical behavior therapy. This therapy focuses on optimizing emotional regulation, distress tolerance, interpersonal effectiveness, and mindfulness skills.
Personality traits are patterns of thoughts, feelings, and behaviors that remain relatively stable over a person’s life and strongly influence how people interact with and perceive the world. Personality disorders are personality traits that cluster in recognizable patterns and produce dysfunction in multiple areas of life. They do not respond well to pharmacologic interventions but are often accompanied by other psychiatric comorbidities. Recognizing personality disorders can help a provider avoid misdiagnosing psychiatric conditions, anticipate future care challenges, and counsel family and caregivers.
Psychological Wellbeing Practitioners (PWPs) are central to NHS Talking Therapies services for depression and anxiety (TTad; formerly ‘IAPT’). This workforce has been trained to deliver low-intensity treatments for mild to moderate depression and anxiety. In practice, PWPs routinely work with more complex clients, likely due to a combination of reasons. Over half of referrals experience concurrent personality difficulties, which are linked to poorer treatment outcomes, and PWPs describe feeling unskilled to work with these clients. This study aimed to develop and pilot a Continuing Professional Development workshop for PWPs about enhancing practice in the context of concurrent personality difficulties; and evaluate acceptability, feasibility and potential impacts on clinical skills and attitudes. This is an audit of routine feedback from a pilot of the workshop offered in a single TTad PWP workforce (n=139). The workshop was successfully developed and a series of five workshops were delivered to 74% of the PWP workforce. Feedback was overwhelmingly positive, and a majority of PWPs reported improved confidence in key skills covered during the workshop, and a positive attitude towards working with clients with personality difficulties after the workshop. PWPs described enhanced capability, opportunity and motivation to undertake work with this client group following the workshop. The workshop showed potential to improve PWP confidence and skill to support TTad clients in the context of personality difficulties, although it is not yet known if this translates to better treatment outcomes for clients. Implications for practice and future research are discussed.
Key learning aims
(1) Understand the feasibility of gathering feedback and outcome data of a Continuing Professional Development (CPD) workshop delivered in routine practice for PWPs.
(2) Understand PWP perspectives on attending a CPD workshop to support tailoring PWP treatments for depression and anxiety in the context of personality difficulties.
(3) Reflect on potential opportunity to enhance PWP treatments in the context of personality difficulties via brief training workshops.
(4) Consider how COM-B can be used to explore barriers and enablers to PWPs implementing new learning to their practice.
Personality disorders can worsen with age or emerge after a relatively dormant phase in earlier life when roles and relationships ensured that maladaptive personality traits were contained. They can also be first diagnosed in late life, if personality traits become maladaptive as the person reacts to losses, transitions and stresses of old age. Despite studies focusing on late-life personality disorders in recent years, the amount of research on their identification and treatment remains deficient. This article endeavours to provide an understanding of how personality disorders present in old age and how they can be best managed. It is also hoped that this article will stimulate further research into this relatively new field in old age psychiatry. An awareness of late-life personality disorders is desperately needed in view of the risky and challenging behaviours they can give rise to. With rapidly growing numbers of older adults in the population, the absolute number of people with a personality disorder in older adulthood is expected to rise.
Much research has focused on executive function (EF) impairments in psychopathy, a severe personality disorder characterized by a lack of empathy, antisocial behavior, and a disregard for social norms and moral values. However, it is still unclear to what extent EF deficits are present across psychopathy factors and, more importantly, which EF domains are impaired. The current meta-analysis answers these questions by synthesizing the results of 50 studies involving 5,694 participants from 12 different countries. Using multilevel random-effects models, we pooled effect sizes (Cohen's d) for five different EF domains: overall EF, inhibition, planning, shifting, and working memory. Moreover, differences between psychopathy factors were evaluated. Our analyses revealed small deficits in overall EF, inhibition, and planning performance. However, a closer inspection of psychopathy factors indicated that EF deficits were specific to lifestyle/antisocial traits, such as disinhibition. Conversely, interpersonal/affective traits, such as boldness, showed no deficits and in some cases even improved EF performance. These findings suggest that EF deficits are not a key feature of psychopathy per se, but rather are related to antisociality and disinhibitory traits. Potential brain correlates of these findings as well as implications for future research and treatment are discussed.
Prominent clinical perspectives posit that the interface of autism and (borderline) personality disorder manifests as either a misdiagnosis of the former as the latter or a comorbidity of both. In this editorial, we integrate these disparate viewpoints by arguing that personality difficulties are inherent to the autistic spectrum.
Edited by
David Kingdon, University of Southampton,Paul Rowlands, Derbyshire Healthcare NHS foundation Trust,George Stein, Emeritus of the Princess Royal University Hospital
This chapter considers how to care for patients who meet the criteria for a diagnosis of personality disorder. We reflect on the role of the psychiatrist in creating a resilient, honest and caring clinical environment, delivering interventions in a considered and coherent manner. Central to this is the relationship between doctor and patient, which includes not only direct clinical care but also the orchestration of work across the multi-disciplinary team and other agencies through clinical leadership.
We approach personality disorders as a relational problem in which the patient experiences their difficulties through their relationships with themselves and the world around them. These difficulties often, though not exclusively, are a developmental consequence of adverse childhood experiences, brought to life within the therapeutic relationship itself. This inevitably means the work is challenging, but it also means that the way we comport ourselves and lead becomes central to the therapeutic culture.
Much has been written on the challenges of working with people who are diagnosable with personality disorder, but perhaps less acknowledged is how these challenges represent not only the very material fundamental to our primary task but also the reason it is such rewarding work given the right circumstances.
Edited by
David Kingdon, University of Southampton,Paul Rowlands, Derbyshire Healthcare NHS foundation Trust,George Stein, Emeritus of the Princess Royal University Hospital
Personality disorder represents a diagnosis very different from others in psychiatry. This is because it describes a long-standing integral part of a person, not just an affliction that has happened. Because of the sensitivity of ascribing a core part of a person’s being to the impersonality of a diagnostic term, the subject has been widely stigmatised. However, the condition is very common and affects one-tenth of the population. In this chapter, the clinical features of personality disorder identified in the new ICD-11 severity classification are described and their value illustrated. A fuller description of the ICD-11 classification can be found in another College publication.
There are five levels of diagnosis of personality disorder, including the sub-syndromal form – personality difficulty – which is by far the most common. The diagnosis of borderline personality disorder is the most used in practice but is a heterogeneous term that overlaps with almost every other disorder in psychiatry. All personality disorders have approximately equal genetic and environmental precursors, and the involvement of childhood adverse experiences and trauma is unfortunately true for this as for all psychiatric disorders.