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To assess the association between coffee consumption and life expectancy among the US adults.
Design:
Prospective cohort.
Setting:
National representative survey in the United States, 2001–2018.
Participants:
A total of 43 114 participants aged 20 years or older with complete coffee consumption data were included from National Health and Nutrition Examination Survey 2001–2018.
Results:
Over a median follow-up of 8·7 years, 6234 total deaths occurred, encompassing 1929 deaths from CVD and 1411 deaths from cancer. Based on the nationally representative survey, we found that coffee consumption is associated with longer life expectancy. The estimated life expectancy at age 50 was 30·06 years (95 % CI, 29·68, 30·44), 30·82 years (30·12, 31·57), 32·08 years (31·52, 32·70), 31·24 years (30·29, 32·19), and 31·45 years (30·39, 32·60) in participants consuming 0, ≤ 1, 1 to ≤ 2, 2 to ≤ 3, and > 3 cups of coffee per day, respectively. Consequently, compared with non-coffee drinkers, participants who consumed 1 to ≤ 2 cups/day had a gain of 2·02 years (1·17, 2·85) in life expectancy on average, attributable to a 0·61-year (29·72 %) reduction in CVD deaths. Similar benefits were found in both males and females.
Conclusion:
Our findings suggest that moderate coffee consumption (approximately 2 cups per day) could be recommended as a valuable component of a healthy diet and may be an adjustable effective intervention measure to increase life expectancy.
This chapter examines how property regimes are likely to respond to the significant increase in average life expectancy predicted by “100-year life” theories. It takes a relatively pessimistic position, arguing that the optimal institutional response to demographic aging will be very difficult to produce: some countries, most notably the US, are likely to underrespond to the socioeconomic demands that demographic aging will probably impose on property law, whereas others, such as China and Japan, may well overrespond. This is because, within the realm of property rights and regulation, the economics and politics of demographic aging may well contradict each other: aging potentially reinforces political opposition to public governance even as it creates economic demand for it.
There are two barriers to realizing the promise of the 100-year life in the US. The first is that few get to live it: unlike peers in other high-income countries, the life expectancy of Americans is short. Paradoxically, however, boosting American longevity would aggravate a second problem: on important dimensions, Americans enjoy less independence in old age than their peers. These problems have something perhaps unexpected in common: a built environment that requires driving as the price of first-class citizenship. That bargain, a legacy of twentieth-century transportation and land use policy, first lops years off of life expectancy by claiming lives at disproportionately young ages and then saps independence and quality of life among the small share of Americans who are fortunate to reach very old age. This chapter proposes two solutions. First, it urges road safety interventions that maximize life expectancy and thus expand the promise of the 100-year life. Second, it develops a variant on the classic Tiebout model of residential sorting that applies the concept more narrowly to enable retirees to thrive (transportation-based “gray Tiebout sorting”). It details the instrumental promise of such a market and its potential for broad spillover benefits.
Lynda Gratton and Andrew Scott’s prediction that the median lifespan will exceed 100 years for children born today in high-income countries is “science fiction” within the dictionary definition: a “story featuring hypothetical scientific or technological advances.” This chapter argues that for a 100-year life to become the norm within the timeframe that Gratton and Scott envision, we will need to make extraordinary progress over the next several decades in reducing old-age mortality – advances that are qualitatively different from the disease-specific innovations that attract the vast majority of biomedical investment today. To achieve those advances will require not only scientific ingenuity but also legal and political innovation. Patent law – the most familiar tool in the innovation policy toolkit – is ill-fitted for the goal of attaining century-long lives. Instead of relying on private-sector sources, we will likely need governments to commit to moonshot investments in longevity akin to the Apollo project. Yet securing support for those investments will be challenging given the political economy of public funding for biomedical research. Thus the path to a 100-year life will likely require major breakthroughs not only in the laboratory but also in the legislature.
In the mid-twentieth century, income and wealth inequality was declining, leading to an era of comparative economic equality and a large middle class. But since the early 1980s, income and wealth inequality has been on the rise. The 100-year life describes how increasing life expectancy could transform the course of individual lives in detail – but how does this trend intersect with our age of inequality? And what does it mean for law and policymaking more generally? The dark side of rising life expectancy is that it is unequally shared. The first part of this chapter briefly discusses how age and inequality are connected – that is, that not everyone shares in rising life expectancy equally and that those who are living longer share many common attributes. The second part considers the possible impact of the skew in rising life expectancy on representative government. Inequality skews politics to favor the wealthy; inequality by age will likely do the same. The fundamental problem is that power is held unequally in most societies. The third part, on age and institutional design, outlines some ways in which political structures might be crafted to account for age-related differences.
People with severe mental illness (SMI) have a higher risk of premature mortality than the general population.
Aims
To investigate whether the life expectancy gap for people with SMI is widening, by determining time trends in excess life-years lost.
Method
This population-based study included people with SMI (schizophrenia, bipolar disorder and major depression) alive on 1 January 2000. We ascertained SMI from psychiatric hospital admission records (1981–2019), and deaths via linkage to the national death register (2000–2019). We used the Life Years Lost (LYL) method to estimate LYL by SMI and sex, compared LYL to the Scottish population and assessed trends over 18 3-year rolling periods.
Results
We included 28 797 people with schizophrenia, 16 657 with bipolar disorder and 72 504 with major depression. Between 2000 and 2019, life expectancy increased in the Scottish population but the gap widened for people with schizophrenia. For 2000–2002, men and women with schizophrenia lost an excess 9.4 (95% CI 8.5–10.3) and 8.2 (95% CI 7.4–9.0) life-years, respectively, compared with the general population. In 2017–2019, this increased to 11.8 (95% CI 10.9–12.7) and 11.1 (95% CI 10.0–12.1). The life expectancy gap was lower for bipolar disorder and depression and unchanged over time.
Conclusions
The life expectancy gap in people with SMI persisted or widened from 2000 to 2019. Addressing this entrenched disparity requires equitable social, economic and health policies, healthcare re-structure and improved resourcing, and investment in interventions for primary and secondary prevention of SMI and associated comorbidities.
A fundamental problem in descriptive epidemiology is how to make meaningful and robust comparisons between different populations, or within the same population over different periods. The problem has several dimensions. First, the data we have to work with (e.g. incident and prevalent cases, and deaths) is rarely usable in its raw form. We must therefore transform it in some way before undertaking the comparison itself. Second, our data usually tells us about fundamentally different attributes of the populations we are seeking to compare. If we are only ever interested in comparing any one of these attributes at a time (mortality, for example), then one of several simple and well-established transformations is all that is typically required. Increasingly, however, epidemiologists are being asked to bring these attributes together into more integrated and meaningful comparisons.
Geriatric (old age) psychiatry faces growing challenges amid Europe’s ageing population. This editorial emphasises the need for specialised training, mentorship and subspecialty recognition to attract young psychiatrists. By addressing structural gaps and fostering innovation, the field offers a rewarding career in enhancing older adults’ mental healthcare and quality of life.
In recent decades, analysing the progression of mortality rates has become very important for both public and private pension schemes, as well as for the life insurance branch of insurance companies. Traditionally, the tools used in this field were based on stochastic and deterministic approaches that allow extrapolating mortality rates beyond the last year of observation. More recently, new techniques based on machine learning have been introduced as alternatives to traditional models, giving practitioners new opportunities. Among these, neural networks (NNs) play an important role due to their computation power and flexibility to treat the data without any probabilistic assumption. In this paper, we apply multi-task NNs, whose approach is based on leveraging useful information contained in multiple related tasks to help improve the generalized performance of all the tasks, to forecast mortality rates. Finally, we compare the performance of multi-task NNs to that of existing single-task NNs and traditional stochastic models on mortality data from 17 different countries.
Nearly 3% of adults have attention-deficit and hyperactivity disorder (ADHD), although in the UK, most are undiagnosed. Adults with ADHD on average experience poorer educational and employment outcomes, worse physical and mental health and are more likely to die prematurely. No studies have yet used mortality data to examine the life expectancy deficit experienced by adults with diagnosed ADHD in the UK or worldwide.
Aims
This study used the life-table method to calculate the life-expectancy deficit for people with diagnosed ADHD using data from UK primary care.
Method
A matched cohort study using prospectively collected primary care data (792 general practices, 9 561 450 people contributing eligible person-time from 2000–2019). We identified 30 039 people aged 18+ with diagnosed ADHD, plus a comparison group of 300 390 participants matched (1:10) by age, sex and primary care practice. We used Poisson regression to estimate age-specific mortality rates, and life tables to estimate life expectancy for people aged 18+ with diagnosed ADHD.
Results
Around 0.32% of adults in the cohort had an ADHD diagnosis, ~1 in 9 of all adults with ADHD. Diagnoses of common physical and mental health conditions were more common in adults with diagnosed ADHD than the comparison group. The apparent reduction in life expectancy for adults with diagnosed ADHD relative to the general population was 6.78 years (95% CI: 4.50 to 9.11) for males, and 8.64 years (95% CI: 6.55 to 10.91) for females.
Conclusions
Adults with diagnosed ADHD are living shorter lives than they should. We believe that this is likely caused by modifiable risk factors and unmet support and treatment needs in terms of both ADHD and co-occurring mental and physical health conditions. This study included data from adults with diagnosed ADHD; the results may not generalise to the entire population of adults with ADHD, the vast majority of whom are undiagnosed.
This chapter proposes a framework for estimating the investment in human capital from health improvement or activities that improve life expectancy and reduce morbidity rates. The measurement framework builds on and extends the Jorgenson-Fraumeni income-based approach for estimating human capital to account for the effect of health on human capital. This economic approach to measuring health human capital differs from the welfare-based approach that estimates the economic effect of health improvements on the quality of life and well-being of individuals. The framework is then implemented for Canada, and the investment in health human capital for the period from 1970 to 2020 is estimated. The estimated investment in health human capital based on the income approach was found to be lower than health expenditures in Canada. This suggests that much of the health expenditures should be classified as consumption rather than as an investment that increases earnings.
For decades, researchers have tried to identify ecological and biological correlates of longevity, often using life expectancy and maximum lifespan as the gold standards. The recent increase in demographic data collected in non-model species has also led researchers to develop alternative metrics of longevity, especially in comparative analyses (e.g. 90% longevity). As a result, studies focused on longevity rely on heterogeneous statistical methodologies and use a variety of longevity metrics that are not always clearly defined. This lack of clarity has led to confusion in the interpretation of results and makes it difficult to compare results across studies. This chapter discusses the statistical interpretation of each metric and highlights potential biases associated with the missus of longevity metrics; conducts a systematic review of the various longevity metrics used across the scientific literature and analyses the content of scientific articles on longevity using topic modelling methodology; and illustrates, using two examples, the importance of selecting the appropriate metric based on the research question. Based on these insights, it provides a list of recommendations aimed at helping researchers to think carefully about the choice of metrics when studying longevity.
The Global South, that groups together low- or middle- income countries mainly located in Africa, Asia and Latin America, concentrates most of the world population. Population ageing, caused by the demographic transition and a large decrease in fertility and mortality rates, make these countries face numerous challenges. Among regions in the Global South, the differences in life expectancy at birth were still large in 2022: almost 74 years in Latin America and the Caribbean but only 60 years in sub-Saharan Africa, with some countries barely exceeding 50. Due to many factors that play on health transition, high mortality countries suffer a cumulative burden from both infectious and non-communicable diseases (NCDs). In addition, the lack of old-age mortality data is a dramatic issue when studying longevity in these countries.
Research on schizophrenia and life expectancy has mainly focused on premature mortality.
Aims
This study investigates factors associated with longevity in patients with schizophrenia receiving long-term care and identifies shared traits among these individuals.
Method
A retrospective cross-sectional study analysing the clinical records of 138 patients with schizophrenia who died between 2015 and 2017 in a psychiatric long-term care facility was conducted. Longevity was defined by life tables drawn from the national health database. Variables were compared between longevity and control groups to determine predictors of longer lifespans. Cluster analysis was employed to identify shared traits among individuals with longevity. Causes of death by age were compared.
Results
In the long-term care setting, of the 138 participants, 45 were in the longevity group. This group had more males, lower antipsychotic doses, but more mobility issues. Significant predictors of longevity included older age at onset, longer length of stay, lower activities of daily living scores and a hypertension diagnosis. Cluster analysis revealed two patterns, suggesting that poorer health indicators did not necessarily lead to shorter lives. Fatalities caused by pneumonia were associated with a higher age, compared to those from cancer and choking.
Conclusions
Addressing modifiable risk factors enhances life expectancy in patients with schizophrenia, especially for males, while the age at onset may play a significant role. An integrated long-term care model with close monitoring and timely provision of mental and general healthcare may help extend lifespans. Further research is needed to balance long-term residential care and community-based care for elderly patients with schizophrenia.
Patients prescribed clozapine are increasingly living into old age. However, there is a lack of studies to guide prescribing in this age group. We sought to identify all clozapine patients in Hertfordshire Partnership NHS Foundation Trust over a 5-year period and review side-effect burden and co-prescribing in all patients aged over 65 years.
Results
We identified 69 patients. The majority (61%) were stable in terms of mental state; 94% of cases had experienced a side-effect within the past year, with constipation occurring most commonly (65% of cases).
Clinical implications
Our findings reveal a significant side-effect burden, particularly in relation to constipation. Clozapine-induced gastrointestinal hypomotility (CIGH) can be fatal; however, increasing age has not been a recognised risk factor for constipation in clozapine patients to date. This raises questions about increasing risk to physical health as patients age and adds to concerns about the lack of monitoring for CIGH.
The preventive services at the center of Braidwood Management, Inc. v. Becerra contribute to reducing inequities in life expectancy in the United States. Critical preventive are currently fully covered by insurance as preventive care under the Affordable Care Act. Reducing affordable access to such screenings and medicines is most likely to impact those with lower incomes and less education, and contribute to widening existing inequities in health outcomes.
Recent research has identified a large and growing mortality gap between those with and without college degrees. On average, individuals without college degrees are likely to die about 8.5 years earlier than those with such degrees. In recent decades, cancer death rates fell nearly two times faster among the college educated. Mortality from heart disease fell by nearly two-thirds among those with college degrees but by less than one-third for all others.
Disparities in life expectancy in the United States reflect the uneven progress against the leading causes of death among different populations. The Braidwood decision, if upheld, will raise the costs to patients for interventions that have contributed to recent gains in life expectancy. This Article analyzes the impact of Braidwood on preventive health interventions in the context of growing life expectancy gaps within the United States.
During the nineteenth century, Iberia entered the path towards modern economic growth. Although industrialization occurred later than in other Western European countries, economic progress ultimately led to an unprecedented improvement in the standards of living. This chapter aims to analyse the evolution of such advances and, when possible, compare Iberia with its Western European counterparts. In so doing, it presents several indicators capturing different dimensions of well-being, average income, consumption patterns, height, life expectancy, and a synthetic measure, the Human Development Index (HDI). Income distribution is examined by looking at alternative inequality indicators: Gini coefficient, the extraction ratio and top income shares. Based on this information the long-run evolution of economic inequality is assessed. All in all, the evidence presented shows that economic progress and well-being significantly improved in Iberia since mid-nineteenth century, although this happened at a slower pace than in Western Europe.
The aim of the study was to analyze gender differences in life expectancy free of depressive symptoms among the adult population in Chile between 2003 and 2016. The Sullivan method was used to estimate the total and marginal life expectancy, based on prevalence data from the National Health Survey (2003, 2010 and 2016), and abridged life tables for the Chilean population. There was a compression of morbidity among middle-aged men during the first period and among younger and older women during the last one. Men at all ages could expect to live a higher proportion of their lives without depressive symptoms during the whole period. The gender gap in the proportion of life expectancy free of depressive symptoms reached 10 percent points or more, considering almost all ages and periods. Unemployment and lower education increased the probability of depressive symptoms, and these effects were more marked among women. Public policies should have a gender-sensitive approach to address the gap in depression and the disadvantage experienced by women in life expectancy free of depressive symptoms, considering those dimensions that intersect with gender, such as access to education, employment or income.
That differences in health outcomes exist between groups is unsurprising and, in some cases, seems subject to ‘natural law’. Such ‘common sense’, arguably unavoidable differences are termed ‘health disparities’ – a term usually understood to be value-neutral. By contrast, more complex differences in health outcomes which seem to derive from differences in opportunities or systemic bias are deemed ‘unfair’ and are referred to as ‘health inequalities’ or ‘health inequities’.
This chapter delves further into how we describe health inequalities and different measures and data that illustrate these differences. Causes and mechanisms of inequality are explored, followed by examples of inequality across groups with certain population characteristics, including ethnicity; gender, sexual orientation and gender identity; disability; and socially excluded groups. Finally, approaches and strategies for reducing health inequalities are presented, with potential actions described at the micro-, meso- and macro-levels.
Best places in the world to grow old based on income, employment, health, education, and environment. In Sweden, health has improved in the older population over the last decades, so Sweden’s health care needs have decreased overall. Sweden has the largest health care workforce in the world serving citizens over 65. 94 % of people over 65 live at home! Elders receive in-home assistance when needed. Only 4% of all care—health care or home care-is paid for by patients themselves. Municipal fixers—people who can come and do chores to help reduce falls, such as change a lightbulb. They come to your home. Totally free. If your needs are high enough, someone can come in every two hours around the clock to help care for you—totally without cost to you. High satisfaction. No stigma around dementia. Swedish government develops list of drugs that older people should not be prescribed. Sweden has implemented community-based care and practical approaches to older adult safety.