Igbo-Ora, a town in southwestern Nigeria, is renowned for exceptionally high dizygotic twin birth rates, recording approximately 45 per 1000 live births. This article explores the factors behind this unique phenomenon by critiquing the community’s perceptions and narrative of the factors responsible for the high twinning rate and comparing these perceptions with biomedical hypotheses. Drawing on 6 months of ethnographic fieldwork — participant observation, 81 semistructured interviews, and FGDs — this study documents local narratives that highlight hereditary ‘twin threads’ —; specific foods, notably Ilasa (okra-leaf soup) and cassava meals; environmental qualities of ‘air’ and ‘water’; and divine sanction as factors responsible for the incidence of twin birth in Igbo-Ora. These local narratives are analyzed against certain biomedical perspectives on maternal age and parity effects, putative genetic variants influencing gonadotrophins, and dietary phytoestrogens. The study found that the community resist single-cause explanations for the incidence of twin birth and instead articulates a complementarity of genetic, ecological, dietary, and spiritual factors. This holistic framing contrasts with and complements prevailing genetic and nutritional theories surrounding the incidence of twin birth. The article argues that future genetic and epidemiological investigations in high-twinning populations must be culturally attuned to ensure accurate phenotype definition, ethical engagement, and translational relevance.

The dietary antioxidant quality score (DAQS) is a valid and reliable tool for assessing the overall antioxidant potency of a diet by considering the synergetic effects of dietary antioxidants. Non-alcoholic fatty liver disease (NAFLD) is linked to the imbalance of the body’s oxidant and antioxidant defense system. The objective of the present research was to investigate the possible associations between DAQS and odds of NAFLD in a large population of the Azar cohort study. The present propensity score–matched case–control study was applied to a population of 14 655 individuals. Demographic, anthropometric and dietary data were gathered, and biochemical markers were measured. The DAQS was evaluated based on the daily dietary intake of vitamin E, vitamin A, vitamin C, Se and Zn, compared with the daily recommended intake. The multivariable logistic regression analysis was employed to determine the association between DAQS with NAFLD-related outcomes. After propensity score matching based on age, gender and body mass index (BMI), participants were allocated into NAFLD (n 660) and non-NAFLD (n 1234) groups. Findings indicated significant differences in age, weight, BMI, waist:hip ratio, TAG, HDL-cholesterol and LDL-cholesterol and dietary intake between percentiles of DAQS in NAFLD patients. Nonetheless, no significant associations were observed between DAQS and NAFLD before and after propensity score matching. Comparing the results to prior research underlines the need for a comprehensive approach for exploring the association between dietary antioxidants, serum antioxidant level and biochemical indices in NAFLD, which is essential for the efficient clarification of the underlying mechanisms.

A significant association between tomato consumption and a lower risk of developing hypertension has been reported. In this study, we aimed to investigate the relationship between tomato intake and prehypertension risk among Korean adults. Hypertension was defined according to the criteria established by the Korean Society of Hypertension. The study participants were selected from the Health Examinees cohort study. Tomato consumption was measured using an FFQ and categorised into quintiles based on the amount consumed. Higher tomato consumption was associated with a lower risk of prehypertension in men (hazard ratio (HR) 0·86, 95 % CI 0·80, 0·92, Pfor trend 0·0005). Women in the highest quintile also showed a similar trend (HR 0·94, 95 % CI 0·90, 0·99, Pfor trend 0·0091). Stratified analyses revealed a reduced risk of prehypertension across all subgroups, except underweight individuals and those with a history of alcohol consumption (all Pfor interaction < 0·05). These findings indicate that higher tomato intake may offer potential advantages for managing blood pressure levels.

Accurate assessment of an individual’s diet is vital to study the effect of diet on health. Image-based methods, which use images as input, may improve the reliability of dietary assessment. We developed an iOS application that uses computer vision to identify food from images. This study aimed to assess the accuracy of energy intake (EIapp) estimates from the application by comparing them to estimated energy expenditure (EE) and to the EI estimates from a validated dietary assessment tool, the 24-h recall (EIrecall). Participants were recruited from a randomised controlled trial called He Rourou Whai Painga. Participants recorded all intake over 7 d using the application, which provided a mean daily EI; this was compared to the EI estimated by two 24-h recalls. The EI from the application and the recalls were compared to EE, estimated using indirect calorimetry and wrist-worn accelerometry. EI estimates from the application and the 24-h recalls were lower than EE, with a mean bias of -1814 kJ (95% CI -3012 to -615, p = 0.005) and -1715 kJ (95% CI -3237 to -193, p = 0.029), respectively. The mean bias between EI from the application and the 24-h recall was 783 kJ (95% CI -875 to 2441, p = 0.33). This suggests that the EI estimates from the application are comparable to the 24-h recall method, a validated and widely used tool in nutritional research.

Healthy ageing and longevity have emerged as urgent public health priorities amid global population ageing and declining birth rates. This review synthesises empirical evidence highlighting the essential role of diet and nutrition in preventing chronic diseases and supporting functional independence in later life. The review was organised using a problem-solving approach to address three core questions: ‘What’ evidence links food and nutrition with positive health outcomes; ‘Why’ do specific dietary components affect biological ageing – via mechanisms such as nutrient sensing, inflammation modulation and caloric restriction; and ‘How’ culturally tailored, person-centred dietary interventions should be developed for better adoption. Findings from centenarian populations suggest that low-energy (i.e. foods with low energy density, such as fruit and vegetables, whole grains), nutrient-rich and diverse diets may help prevent or delay age-related diseases, supporting the notion that food could be used as medicine. Moreover, addressing barriers such as food insecurity and limited access to culturally appropriate healthy food options, particularly in low-income and rural communities, is crucial for achieving equitable health outcomes. Finally, the review calls for integrating personalised nutrition strategies into clinical care and public health initiatives. These efforts can enhance healthspan, improve quality of life and reduce the broader social and economic burdens associated with ageing populations.

This review comprehensively examines the current evidence on the dietary management of chronic constipation, and the dietary recommendations presented in clinical guidelines for chronic constipation. Several randomised controlled trials (RCT) have investigated the effect of dietary supplements, foods and drinks in chronic constipation. Systematic reviews and meta-analyses of these RCTs have demonstrated that psyllium supplements, specific probiotic supplements, magnesium oxide supplements, kiwifruits, prunes, rye bread and high mineral water content may be effective in the management of constipation. However, despite the plethora of evidence, current clinical guidelines only offer a limited number of dietary recommendations. The most commonly recommended dietary strategy in clinical guidelines is dietary fibre, followed by senna supplements and psyllium supplements. The least commonly recommended dietary strategies are magnesium oxide, Chinese herbal supplements, prunes and high mineral-content water. Several evidence-based dietary strategies are omitted by current clinical guidelines (e.g. kiwifruits), while some strategies that are recommended are not always supported by evidence (e.g. insoluble fibre supplement). Dietary recommendations in clinical guidelines can also be ambiguous, lacking outcome-specific recommendations and information for appropriate implementation. Future RCTs are needed to assess currently under-investigated dietary approaches that are nevertheless commonly recommended, and future clinical guidelines should include dietary recommendations supported by available evidence.

A Palaeolithic diet is an efficacious dietary approach for glycaemic control in type 2 diabetes. Causal mechanisms are body weight loss and glucometabolic effects from differences in included food groups, macronutrient composition, fibre content, and glycaemic load. The aim was to test the hypothesis that characteristic food group differences between a Palaeolithic and a diabetes diet would cause an effect on glycaemic control when weight was kept stable and diets were matched for macronutrient composition, fibre content and glycaemic load. Adult participants with type 2 diabetes and increased waist circumference were instructed to follow two diets, with or without the food groups cereal grain, dairy products, and legumes, during two periods of 4 weeks separated by a 6-week washout period in a random-order crossover design. The Palaeolithic diet included fruit, vegetables, tubers, fish, shellfish, lean meat, nuts, eggs and olive oil, and excluded cereal grains, dairy products and legumes. The diabetes diet included fruit, vegetables, fish, shellfish, lean meat, nuts, eggs, olive oil, and substantial amounts of whole grains, low-fat dairy products and legumes. Dietary energy content was adjusted throughout the study to maintain stable body weight. There were no differences between diets on HbA1c or fructosamine among the 14 participants. Body weight was kept stable, and the two diets were successfully matched for macronutrient composition and glycaemic load but not for fibre content. Characteristic food group differences and the accompanying differences in fibre content between a Palaeolithic and a diabetes diet do not cause an effect on glycaemic control.

Parkinson’s disease (PD) is the fastest-growing neurological condition in the world, affecting 11·8 million people worldwide in 2021. Due to the globally expanding and ageing population, as well as growing industrialisation, this number is likely to increase. Given the absence of disease-modifying pharmacological therapies, this review aimed to examine the effect of dietary interventions on PD progression, motor symptoms, non-motor symptoms, specifically those affecting the gastrointestinal (GI) tract, and severity. To do so, this review synthesised the current evidence from randomised controlled trials (RCTs) on dietary patterns, individual foods and beverages, and nutritional supplements including nutrients, bioactive compounds, and biotics.

Results from the included RCTs failed to demonstrate conclusive evidence for the use of a dietary intervention as a therapy for improving PD progression, symptoms and severity. However, this is likely a reflection of the current scarcity of RCTs in the literature, rather than an outright demonstration of the ineffectiveness of such dietary approaches. In contrast, several trials have demonstrated a beneficial effect of biotic supplementation in managing GI symptoms, particularly constipation syndrome, which may be a promising avenue for improving GI-related issues that affect up to 80 % of PD patients. In conclusion, further RCTs are required to decipher the role that diet may play in mitigating PD progression and severity and improving overall patient care by reducing both motor and non-motor symptoms.

During the global recession of 2020 food insecurity increased substantially in many countries around the world. Fortunately, the surge in food insecurity quickly came to a halt as the world economy returned to its positive growth path, despite double-digit domestic food inflation in most countries. To shed light on the relative importance of income growth and food inflation in driving food insecurity, we employ a heterogeneous-agent model with income inequality, complemented by novel cross-country data for the period 2001–2021. We use external instruments (changes in commodity terms-of-trade, external economic growth, and harvest shocks) to isolate exogenous variation in domestic income growth and food inflation. Our findings suggest that income growth is the dominant driver of annual variations in food insecurity, while food price inflation plays a somewhat smaller role, aligning with our model predictions.

Coastal wetlands, known for their remarkable productivity and diverse ecological functions, face growing threats from aquaculture expansion, which can fragment natural habitats and disrupt water flow. In this study, we focused on White-bellied Sea-Eagles Haliaeetus leucogaster along the eastern coast of Odisha, India, to see how these top predators adapt to accelerating aquaculture. Across 22 nesting sites over three breeding seasons (2021–2024), we analysed 3,319 prey items, and found that fish dominated at 66.89%, followed by birds (25.64%), reptiles (3.31%), invertebrates (3.16%), and mammals (0.99%). Using generalised additive models (GAMs), we evaluated various landscape factors influencing the proportion of fish in WBSE diets. Our results revealed that shorter distances to natural water-bodies and higher water coverage strongly influenced higher fish intake, while aquaculture-related variables did not increase fish consumption. These patterns indicate that WBSEs favour wild fish in less-disturbed wetlands, likely because of better energy returns, lower risks, and convenient perching spots. Consequently, our findings highlight the need to safeguard natural aquatic habitats for sustaining apex predators and point to ways of reconciling aquaculture growth with wetland conservation. By clarifying how the eagles respond to changes in coastal landscapes, we offer key insights for preserving biodiversity under fast-paced environmental transformation.

Masters athletes tend to have higher intakes of calcium, magnesium, iron, and zinc when compared to Australian national population data from similar age groups(1). However, little is known about the diets of New Zealand Olympians as they get older. This study aimed to describe the micronutrient intakes of New Zealand Olympic and Commonwealth Games athletes over the age of 60 years and make comparisons with National Nutrition Survey data. Thirty-three individuals (mean age 76±8 years, n=27 male) who had represented New Zealand at an Olympic or Commonwealth Games participated in this study. Dietary intake was assessed using three 24-h diet recalls. The first recall was conducted face to face in the participant’s home and the second and third were completed over a voice or video call on non-consecutive days following this. All recalls were performed using a multiple-pass technique and entered into FoodWorks dietary analysis software (Version 9, Xyris Software Ltd., Brisbane, Australia). Mean intakes across the three recalls were used to represent the intake of each individual.This study was approved by the University of Otago Ethics Committee (Health; H23/054, April 2023).The mean intakes of iron (males 13.3±5.1 mg, females 9.9±1.9 mg) and zinc (males 10.7±4.0 mg, females 9.6±1.9 mg) in Olympians were similar to those reported in those over 70 y in the 2008/09 New Zealand Adult Nutrition Survey, but more than 60% of Olympians had intakes below the estimated average requirements for these nutrients. Intakes of calcium (males 1048±474 mg, females 810±139 mg) and selenium (males 66.7±49.1 µg, females 48.4±17.7 µg) were higher in Olympians when compared to the 2008/09 New Zealand Adult Nutrition Survey data, however 39% and 61% of Olympians still had intakes below the estimated average requirements, respectively. While this group of older New Zealand Olympians did have higher intakes of some nutrients than a representative sample of their peers, a marked number are still at risk of inadequate intakes and may benefit from a nutrition intervention to improve the overall quality and adequacy of their diet.

This review highlights the importance of dietary fibres (DF) intake and its interconnection with the gut microbiome and psychological well-being, while also exploring the effects of existing DF interventions on these aspects in adults. The gut microbiota is a complex and diverse ecosystem in which microbial species interact, influencing the human host. DF are heterogeneous, requiring different microbial species to degrade the complex DF structures. Emerging evidence suggests that microbial fermentation of DF produces short-chain fatty acids (SCFA), which may play a role in regulating psychological well-being by affecting neurotransmitter levels, including serotonin. The effectiveness of DF interventions depends on factors such as baseline gut microbiota composition, the dosage and the source of DF consumed. Although the gut microbiota of adults is relatively stable, studies have shown that the abundance of the species in the gut microbiota can change within 24 h of an intervention and may return to baseline following the termination of DF intervention. This review underscores the need for larger and well-powered dietary clinical trials incorporating longitudinal biological sample collections, advanced sequencing and omic techniques (including novel dietary biomarkers and microbial metabolites), validated subjective questionnaires and dietary records. Furthermore, mechanistic studies driven by clinical observations are crucial to understanding gut microbiota function and its underlying biological pathways, informing targeted dietary interventions.

There has been substantial research undertaken on the role of a health-promoting diet in depression. Yet, the evidence of the relationship between the Nordic diet and the risk of depression is scarce. This cross-sectional study aimed to assess whether a healthy Nordic diet is associated with depressive symptoms. In total, 2603 men aged 42–60 years from the Kuopio Ischaemic Heart Disease Risk Factor Study were included. Diet quality was evaluated with a healthy Nordic diet score derived from the 4-day food diaries and depressive symptoms with the self-reported Human Population Laboratory (HPL) depression scale. Quade ANCOVA was used to examine the mean values of HPL scores in quartiles of a healthy Nordic diet score. Participants’ mean age was 53 years and BMI 26·8 kg/m2; 31·7 % were current smokers, and 86·9 % were married or living as a couple. The mean healthy Nordic diet score was 12·8 (sd 4·0, range 2–25), and the mean HPL depression score was 1·9 (sd 2·1, range 0–13). The findings suggested that lower adherence to a healthy Nordic diet was associated with higher HPL depression scores after adjusting for age, examination year, daily energy intake, leisure-time physical activity, adulthood socio-economic status, smoking and marital status (extreme quartile difference: 0·33 points, 95 % CI 0·10, 0·56, P for trend across the quartiles = 0·003). The results support the hypothesis that a lower-quality diet increases the odds of having depressive symptoms. However, prospective studies are needed to confirm the association.

Phase Angle (PhA) has emerged as an important parameter to monitor body composition, fluid status, muscle integrity, and physical performance among athletes. However, limited information exists regarding the associations between PhA and dietary intake, especially in athletes. This study aimed to identify the dietary intake components associated with PhA in athletes. This cross-sectional observational study was carried out with 153 athletes across 17 sports. Body composition was assessed by tetrapolar multifrequency BIA, and dietary intake by 24-hour dietary recalls administered on non-consecutive days. Reported foods and supplements were categorised into different groups (i.e. cereals, vegetables, fruits, beans and nuts, meat and eggs, dairy products, oils, and sugars), with portions established based on the food’s total energy content. Fat-free mass and fat-free mass index were higher in male compared to female athletes, potentially influencing PhA (6.6º vs 5.5º; P < 0.01). Multiple linear regression analysis indicated that protein intake was a significant predictor of PhA in athletes. This association remained significant even after adjustments for sex, age, and fat-free mass (R2 = 0.48, β = 0.27, P = 0.02). The positive correlation observed between dietary protein and PhA reinforces the need for adequate daily protein intake to enhance PhA in athletes. Further studies investigating the effect of diet-induced changes in PhA within the athletic population are necessary.

The recovery of nearly 250 burials at the El Olivar site provided the opportunity to address questions regarding the groups inhabited coastal settings of the semiarid north of Chile between the 800 and 1540 AD. Stable isotopes of carbon, nitrogen, and oxygen were analyzed from 60 human samples. Radiocarbon (14C) analyses were conducted in 20 samples from camelids and 42 human samples. Subsequently, a sample of 25 individuals exhibiting diagnostic cultural features of the Las Ánimas Cultural Complex (LACC) and the Chilean Diaguita Culture (CDC) was selected for the purpose of assessing differences in their diet and mobility and clarifying their chronology. The δ13C and δ15N values obtained revealed the existence of a small group of individuals (n=6) with a diet based on C3 plants and terrestrial protein, and another major group (n=33) with values compatible with the consumption of C4 plants and marine resources. Four of the six individuals of the small group presented Ánimas diagnostic features, and in the major group were identified both Ánimas and Diaguita individuals. The δ18O values exhibited a similarity between the Ánimas and Diaguita individuals, suggesting coastal-to-inland mobility in both groups. Calibrated 14C dates indicate that El Olivar was occupied for a period of nearly 380 years, spanning between 1150 and 1536 AD, and that between the 1300 and 1400 AD, Ánimas and Diaguita individuals coexisted at El Olivar. These findings call into question the current thought that the CDC emerged from the LACC around 1000 AD, and that both represent different archaeological entities.