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Acute phase proteins: a review of their function, behaviour and measurement in chickens

Published online by Cambridge University Press:  27 February 2014

E.L. O'REILLY  and
P.D. ECKERSALL
E.L. O'REILLY*
Affiliation:
Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow, G61 1QH, United Kingdom
P.D. ECKERSALL
Affiliation:
Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow, G61 1QH, United Kingdom
*
Corresponding author: e.o'reilly1@research.gla.ac.uk
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Abstract

This review brings together and consolidates the large amount of research on acute phase proteins (APPs) that has been undertaken in chickens. Acute phase proteins are secreted from the liver as a result of inflammation or infection that can be measured in plasma. They have been well-characterised in other farm animal species and have been measured in a wide variety of poultry research areas. The acceleration in chicken APP research is in response to increased interest in ways the immune responses of the chicken can be measured and compared during infection or environmental or nutritional changes. All APPs that have been identified and characterised in chickens are described in the following review and their responses during infection discussed. The APPs are tabulated with basal values and classification to provide a comparative and useful reference. The ways APPs can be measured in chickens and the assays available are also described. This review will detail the functions of the positive APPs in chickens and their behaviour during an APR.

Keywords

chickenacute phase proteinbiomarkerinfection

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Type
Review Article
Information
World's Poultry Science Journal , Volume 70 , Issue 1 , March 2014 , pp. 27 - 44
Copyright
Copyright © World's Poultry Science Association 2014 

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