Hostname: page-component-7dd5485656-g8tfn Total loading time: 0 Render date: 2025-10-30T07:43:54.369Z Has data issue: false hasContentIssue false
  • English
  • Français

Study of the effects of insulin on the migration of Hymenolepls diminuta in rats

Published online by Cambridge University Press:  05 June 2009

C. H. Cho
C. H. Cho
Affiliation:
Laboratory of Pharmacology, Department of Medical Research, Veterans General Hospital, Taipei, Taiwan, Republic of China
Get access Rights & Permissions [Opens in a new window]

Abstract

The effects of insulin on worm (Hymenolepls diminuta) migration was studied. Insulin injection (20 U/kg, s.c.) significantly increased gastric acid output but did not affect the serotonin content of blood, intestinal lumen or worms. The drug produced, dose-dcpcndcntly, postcriad migration of the worms in rats without pylorusligation but ligation of the pylorus prevented this migration. It is concluded that the hypcrsccrction of gastric acid induced by insulin is responsible for the postcriad migration of H. diminuta in rats.

Information

Type
Research Article
Information
Journal of Helminthology , Volume 58 , Issue 4 , December 1984 , pp. 291 - 293
Copyright
Copyright © Cambridge University Press 1984

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

REFERENCES

Cho, C. H. (1982) Cholincrgic activation of 5-HT release from small intestine during food-feeding. Chinese Journal of Physiology, 25, 97–102.Google Scholar
Cho, C. H. & Mettrick, D. F. (1980) Vagal stimulation, 5-HT and migratory behaviour of Hymcnolepis diminuta in the rat intestine. Physiologist, 23, 39.Google Scholar
Cho, C. H. & Mettrick, D. F. (1982) Orcadian variation in the distribution of Hymenolepis diminuta (Ccstoda) and 5-hydroxytryptaminc levels in the gastrointestinal tract of the laboratory rat. Parlsitology, 84, 431–441.CrossRefGoogle Scholar
Ciarlone, A. E. (1976) Modification of spcctrophotofluoromctric method of analyzing serotonin, norcpincphrinc and dopaminc in one brain sample. Microchemlcal Journal, 21, 349–355.CrossRefGoogle Scholar
Kim, K. S. & Shore, P. A. (1963) Mechanism of action of rcscrpinc and insulin on gastric amines and gastric acid secretion, and the effect of monoaminc oxidasc inhibition. Journal of Pharmacology and Experimental Therapeutics, 141, 321–325.Google Scholar
Mettrick, D. F. (1971) Effect of host dietary constituents on intestinal pH and on the migration behaviour of the rat tapeworm Hymenolepis diminuta. Canadian Journal of Zoobgy, 49, 1513–1524.CrossRefGoogle ScholarPubMed
Mettrick, D. F. & Cho, C.H. (1981 a) Effect of electrical vagal stimulation on migration Hymenolepis diminuta. Journal of Parasitology, 67, 386–390.CrossRefGoogle ScholarPubMed
Mettrick, D. F., Cho, C. H. (1981 b) Migration of Hymcnolepis diminuta (Ccstoda) and changes in 5-HY (serotonin) levels in the rat host following parenteral and oral 5-HT administration. Canadian Journal of Physiology and Pharmacology, 59, 281–286.CrossRefGoogle Scholar
Mettrick, D. F. & Cho, C. H. (1982) Changes in tissue and intestinal serotonin (5-HT) levels in the laboratory rat following feeding and the effect of 5-HT inhibitors on the migratory responses of Hymenolepis diminuta (Cestoda). Canadian Journal of Zoology, 60, 790–797.CrossRefGoogle Scholar
Podesta, R. P. & Mettrick, D. F. (1981) A simple method for analyzing oral and intravenous treatment effects on biomass redistribution of Hymenolepis diminuta in the rat intestine. Canadian Journal of Zoology, 59, 861–865.CrossRefGoogle Scholar
Read, C. P. & Kilejian, A. Z. (1969) Circadian migratory behaviour of a cestodc symbiote in the rat host. Journal of Parasitology, 55, 574–581.CrossRefGoogle ScholarPubMed