Hostname: page-component-7f64f4797f-fz5kh Total loading time: 0 Render date: 2025-11-09T21:50:21.467Z Has data issue: false hasContentIssue false
  • English
  • Français

Polypropylene microplastics affect the physiology in Drosophila model

Published online by Cambridge University Press:  13 January 2023

Hao Tang ,
Lichao Zhong ,
Yifan Xu ,
Zhishen Jin ,
Zhihao Pan  and
Jie Shen Open the ORCID record for Jie Shen [Opens in a new window]
Hao Tang
Affiliation:
College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China 310018
Lichao Zhong
Affiliation:
College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China 310018
Yifan Xu
Affiliation:
College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China 310018
Zhishen Jin
Affiliation:
College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China 310018
Zhihao Pan
Affiliation:
College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China 310018
Jie Shen*
Affiliation:
College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China 310018
*
Author for correspondence: Jie Shen, Email: shenjie@hdu.edu.cn
Get access Rights & Permissions [Opens in a new window]

Abstract

Microplastics (MPs) pollution has been a hot research topic in recent years. MPs are ubiquitous throughout the ecological environment and are eventually accumulated in organisms through inhalation or ingestion. However, given that MPs are inert pollutants, their effects on organisms are not clear. In previous study, we have investigated the effects of polyethylene terephthalate MPs on physiology of Drosophila. What is the effect of polypropylene microplastics (PP-MPs)? The results of our experiments show that being exposed to high concentration of PP-MPs have significant effect on Drosophila. PP-MPs exposure can significantly increase locomotor activity and shorten the time of group sleep in Drosophila. In the presence of high concentrations of PP-MPs, the triglyceride content was reduced in females and their ability of egg production was affected. However, there was no significant effect on the level of protein and carbohydrate, or on the food intake. Our experimental results can provide some preliminary data for assessing the potential hazard of PP-MPs to other organisms.

Keywords

Drosophilaenergy metabolismlocomotor activitypolypropylene microplasticsreproduction

Information

Type
Research Paper
Information
Bulletin of Entomological Research , Volume 113 , Issue 3 , June 2023 , pp. 355 - 360
Check for updates
Copyright
Copyright © The Author(s), 2023. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Albert, A.Koelmans, Nur Hazimah, Mohamed Nor, Enya, Hermsen, Merel, Kooi, Svenja, M.Mintenig and Jennifer, De France (2019) Microplastics in freshwaters and drinking water: critical review and assessment of data quality. Water Research 155, 410–422.Google Scholar
Anderson Abel de Souza Machado, , Werner, Kloas, Christiane, Zarfl, Hempel, Stefan, Rillig, Matthias C. et al. (2018) Microplastics as an emerging threat to terrestrial ecosystems. Global Change Biology 24, 1405–1416.10.1111/gcb.14020CrossRefGoogle Scholar
Anita, Jemec, Petra, Horvat, Urban, Kunej, Marjan, Bele and Andrej, Kržan (2016) Uptake and effects of microplastic textile fibers on freshwater crustacean Daphnia magna. Environmental Pollution 219, 201–209.Google Scholar
Aryani, D, Khalifa, M A, Herjayanto, M, Solahudin, E A, Rizki, E M, Halwatiyah, W, Istiqomah, H, Maharani, S H, Wahyudin, H and Pratama, G (2021) Penetration of microplastics (polyethylene) to several organs of Nile Tilapia (Oreochromis niloticus). IOP Conference Series. Earth and Environmental Science 715, 12061.CrossRefGoogle Scholar
Barboza, Luís Gabriel Antão, Vieira, Luís Russo, Vasco, Branco, Neusa, Figueiredo, Felix, Carvalho, Cristina, Carvalho, Lúcia, Guilhermino et al. (2018) Microplastics cause neurotoxicity, oxidative damage and energy-related changes and interact with the bioaccumulation of mercury in the European seabass, Dicentrarchus labrax (Linnaeus, 1758). Aquatic Toxicology 195, 49–57.CrossRefGoogle ScholarPubMed
Barboza, Luís Gabriel A., Clara, Lopes, Patrícia, Oliveira, Filipa, Bessa, Vanessa, Otero, Bruno, Henriques, Joana, Raimundo, Miguel, Caetano, Carlos, Vale, Lúcia, Guilhermino et al. (2020) Microplastics in wild fish from North East Atlantic Ocean and its potential for causing neurotoxic effects, lipid oxidative damage, and human health risks associated with ingestion exposure. Science of the Total Environment 717, 134625.CrossRefGoogle Scholar
Browne, Mark A., Awantha, Dissanayake, Galloway, Tamara S., Lowe, David M., Thompson, Richard C. et al. (2008) Ingested microscopic plastic translocates to the circulatory system of the mussel, Mytilus edulis (L.). Environmental Science & Technology 42, 5026–5031.CrossRefGoogle Scholar
Calabrese, EJ, Iavicoli, I, Calabrese, V et al. (2013) Hormesis: its impact on medicine and health. Human & Experimental Toxicology 32, 120–152.CrossRefGoogle ScholarPubMed
Chen, Qiqing, Yin, Daqiang, Jia, Yunlu, Schiwy, Sabrina, Legradi, Jessica, Yang, Shouye, Hollert, Henner et al. (2017) Enhanced uptake of BPA in the presence of nanoplastics can lead to neurotoxic effects in adult zebrafish. Science of the Total Environment 609, 1312–1321.CrossRefGoogle ScholarPubMed
Cole, Matthew, Lindeque, Pennie, Fileman, Elaine, Halsband, Claudia, Galloway, Tamara S. et al. (2015) The impact of polystyrene microplastics on feeding, function and fecundity in the marine copepod Calanus helgolandicus. Environmental Science & Technology 49, 1130–1137.CrossRefGoogle ScholarPubMed
Diogo, Peixoto, Pinheiro, Carlos, Amorim, João, Oliva-Teles, Luís, Guilhermino, Lúcia, Vieira, Maria Natividade et al. (2019) Microplastic pollution in commercial salt for human consumption: a review. Estuarine, Coastal and Shelf Science 219, 161–168.Google Scholar
Drummond-Barbosa, D, Spradling, AC (2001) Stem cells and their progeny respond to nutritional changes during drosophila oogenesis. Developmental Biology 231, 265–278.CrossRefGoogle ScholarPubMed
Fiona, Harvey and Jonathan, Watts (2018) Microplastics found in human stools for the first time. The Guardian 22.Google Scholar
Free, Christopher M., Jensen, Olaf P., Mason, Sherri A., Eriksen, Marcus, Williamson, Nicholas J., Boldgiv, Bazartseren et al. (2014) High-levels of microplastic pollution in a large, remote, mountain lake. Marine Pollution Bulletin 85, 156–163.CrossRefGoogle Scholar
Glade-Wright, Robyn (2019) Plastic gothic: Frankenstein, art and the microplastic monster. eTropic: Electronic Journal of Studies in the Tropics 18, 68–80.CrossRefGoogle Scholar
Goldstein, Miriam C., Titmus, Andrew J., Ford, Michael et al. (2013) Scales of spatial heterogeneity of plastic marine debris in the northeast Pacific Ocean. PLoS ONE 8, 0080020.CrossRefGoogle ScholarPubMed
Goodman, Kerestin E., Hare, Joan T., Khamis, Zahraa I., Hua, Timothy, Sang, Qing-Xiang Amy et al. (2021) Exposure of human lung cells to polystyrene microplastics significantly retards cell proliferation and triggers morphological changes. Chemical Research in Toxicology 34, 1069–1081.CrossRefGoogle ScholarPubMed
Gricourt, L, Mathieu, M, Kellner, K et al. (2006) An insulin-like system involved in the control of Pacific oyster Crassostrea gigas reproduction: hrIGF-1 effect on germinal cell proliferation and maturation associated with expression of an homologous insulin receptor-related receptor. Aquaculture 251, 85–98.CrossRefGoogle Scholar
Haibo, Zhang, Wang, Jiaqing, Zhou, Bianying, Zhou, Yang, Dai, Zhenfei, Zhou, Qian, Chriestie, Peter, Luo, Yongming et al. (2018) Enhanced adsorption of oxytetracycline to weathered microplastic polystyrene: kinetics, isotherms and influencing factors. Environmental Pollution 243, 1550–1557.Google Scholar
Hämer, Julia, Gutow, Lars, Köhler, Angela, Saborowski, Reinhard et al. (2014) Fate of microplastics in the marine isopod Idotea emarginata. Environmental Science & Technology 48, 13451–13458.CrossRefGoogle ScholarPubMed
Hasan, Neaz A., Heal, Richard D, Bashar, Abul, Haquea, Mohammad Mahfjulu et al. (2021) Face masks – protecting the wearer but neglecting the aquatic environment? A perspective from Bangladesh. Environmental Challenges (Prepublish) 4, 100126.CrossRefGoogle Scholar
Huang, Jun-Nan, Wen, Bin, Zhu, Jian-Guo, Zhang, Yan-Shen, Gao, Jian-Zhong, Chen, Zai-Zhong et al. (2020) Exposure to microplastics impairs digestive performance, stimulates immune response and induces microbiota dysbiosis in the gut of juvenile guppy (Poecilia reticulata) – ScienceDirect. Science of the Total Environment 733, 138929.CrossRefGoogle Scholar
Jin, Yuanxiang, Xia, Jizhou, Pan, Zihong, Yang, Jiajing, Wang, Wenchao, Fu, Zhengwei et al. (2018) Polystyrene microplastics induce microbiota dysbiosis and inflammation in the gut of adult zebrafish. Environmental Pollution 235, 322–329.10.1016/j.envpol.2017.12.088CrossRefGoogle ScholarPubMed
Jun, Wang, Li, Yuejiao, Lu, Lin, Zheng, Mingyi, Zhang, Xiaona, Tian, Hua, Wang, Wei, Ru, Shaoguo et al. (2019) Polystyrene microplastics cause tissue damages, sex-specific reproductive disruption and transgenerational effects in marine medaka (Oryzias melastigma). Environmental Pollution 254, 113024.Google Scholar
Kosuke, Tanaka, Hideshige, Takada, Yamashita, Rei, Mizukawa, Kaoruko, Fukuwaka, Masa-aki, Watanuki, Yutaka et al. (2013) Accumulation of plastic-derived chemicals in tissues of seabirds ingesting marine plastics. Marine Pollution Bulletin 69, 219–222.Google Scholar
Lei, Lili, Liu, Mengting, Song, Yang, Lu, Shibo, Hu, Jiani, Cao, Chengjin, Xie, Bing, Shi, Huahong, He, Defu et al. (2018) Polystyrene (nano)microplastics cause size-dependent neurotoxicity, oxidative damage and other adverse effects in Caenorhabditis elegans. Environmental Science Nano 5, 10.1039.C8EN00412A-.Google Scholar
Leslie, Heather A., Velzen, Martin J.M.van, Brandsma, Sicco H., Vethaaka, A. Dick, Garcia-Vallejo, Juan J., Lamoree, Marja H. et al. (2022) Discovery and quantification of plastic particle pollution in human blood. Environment International 163, 107199.CrossRefGoogle ScholarPubMed
Letteron, P., Brahimi-Bourouina, N., Robin, M. A., Moreau, A., Feldmann, G. , Pessayre, D. et al. (1997) Glucocorticoids inhibit mitochondrial matrix acyl-CoA dehydrogenases and fatty acid beta-oxidation. American Journal of Physiology 272, 1141–1150.Google ScholarPubMed
Liu, Xiaoyan, Zhao, Yingcan, Dou, Jiabin, Hou, Qinghong, Cheng, Jinxiong, Jiang, Xingyu et al. (2022) Bioeffects of inhaled nanoplastics on neurons and alteration of animal behaviors through deposition in the brain. Nano Letters 22, 1091–1099.CrossRefGoogle ScholarPubMed
Li, Dunzhu, Shi, Yunhong, Yang, Luming, Xiao, Liwen, Kehoe, Daniel K., Gun’ko, Yurii K., Boland, John J., Wang, Jing Jing et al. (2020a) Microplastic release from the degradation of polypropylene feeding bottles during infant formula preparation. Nature Food 1, 746–754.CrossRefGoogle Scholar
Li, Dunmei, Yang, Guangrong, Dou, Pengpeng, Qian, Shenhua, Zhao, Liang, Yang, Yongchuan, Fanin, Nicolas et al. (2020b) Microplastics negatively affect soil fauna but stimulate microbial activity: insights from a field-based microplastic addition experiment: microplastics affect soil biota. Proceedings of the Royal Society B: Biological Sciences 287, :20201268.Google Scholar
Lu, Yifeng, Zhang, Yan, Deng, Yongfeng, Jiang, Wei, Zhao, Yanping, Geng, Jinju, Ding, Lili, Ren, Hongqiang et al. (2016) Uptake and accumulation of polystyrene microplastics in zebrafish (Danio rerio) and toxic effects in liver. Environmental Science & Technology 50, 4054–4060.CrossRefGoogle ScholarPubMed
Maddah, Hisham A. (2016) Polypropylene as a promising plastic: a review. American Journal of Polymer Science 6, 1–11.Google Scholar
Massoulié, Jean, Pezzementi, Leo, Bon, Suzanne, Krejci, Eric, Vallette, François-Marie et al. (1993) Molecular and cellular biology of cholinesterases. Progress in Neurobiology 41, 31–91.CrossRefGoogle ScholarPubMed
Mato, Yukie, Isobe, Tomohiko, Takada, Hideshige, Kanehiro, Haruyuki, Ohtake, Chiyoko, Kaminuma, Tsuguchika et al. (2001) Plastic resin pellets as a transport medium for toxic chemicals in the marine environment. Environmental Science & Technology 35, 318–324.CrossRefGoogle ScholarPubMed
Moslem, Sharifinia, Bahmanbeigloo, Zahra Afshari, Keshavarzifard, Mehrzad, Khanjani, Mohammad Hossein, Lyons, Brett P. et al. (2020) Microplastic pollution as a grand challenge in marine research: a closer look at their adverse impacts on the immune and reproductive systems. Ecotoxicology and Environmental Safety 204, 111109.Google Scholar
Nagao, M, Parimoo, B, Tanaka, K et al. (1993) Developmental, nutritional, and hormonal regulation of tissue-specific expression of the genes encoding various acyl-CoA dehydrogenases and alpha-subunit of electron transfer flavoprotein in rat. Journal of Biological Chemistry 268, 24114–24124.CrossRefGoogle ScholarPubMed
Neckameyer, WS and Cooper, RL (1998) GABA transporters in Drosophila melanogaster: molecular cloning, behavior, and physiology. Invertebrate Neuroscience 3, 279–294.Google ScholarPubMed
Rana, A, Rera, M., Walker, D.W. Rana, A. | , | , (2013) Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan. Proceedings of the National Academy of Sciences of the USA 110, 8638–8643.CrossRefGoogle ScholarPubMed
Richard, Wong, Piper, Matthew D. W., Wertheim, Bregje, Partridge, Linda et al. (2009) Quantification of food intake in Drosophila. PLoS ONE 4, e6063.Google Scholar
Setälä, Outi, Fleming-Lehtinen, Vivi, Lehtiniemi, Maiju et al. (2014) Ingestion and transfer of microplastics in the planktonic food web. Environmental Pollution 185, 77–83.Google ScholarPubMed
Shanshan, Zhang, Ding, Jiannan, Razanajatovo, Roger Mamitiana, Jiang, Hang, Zou, Hua, Zhu, Wenbin et al. (2019) Interactive effects of polystyrene microplastics and roxithromycin on bioaccumulation and biochemical status in the freshwater fish red tilapia (Oreochromis niloticus). Science of the Total Environment 648, 1431–1439.Google Scholar
Shaw, Paul J., Cirelli, Chiara, Greenspan, Ralph J., Tononi, Giulio et al. (2000) Correlates of sleep and waking in Drosophila melanogaster. Science (American Association for the Advancement of Science) 287, 1834–1837.CrossRefGoogle ScholarPubMed
Smith, Madeleine, Love, David C., Rochman, Chelsea M., Neff, Roni A. et al. (2018) Microplastics in seafood and the implications for human health. Current Environmental Health Reports 5, 375–386.CrossRefGoogle ScholarPubMed
Sussarellu, Rossana, Suquet, Marc, Thomas, Yoann, Huvet, Arnaud et al. (2016) Oyster reproduction is affected by exposure to polystyrene microplastics. Proceedings of the National Academy of Sciences 113, 2430–2435.CrossRefGoogle ScholarPubMed
Thompson, Richard C., Olsen, Ylva, Mitchell, Richard P. , Davis, Anthony, Rowland, Steven J., John, Anthony W. G. , Mcgonigle, Daniel et al. (2004) Lost at sea: where is all the plastic? Science 304, 838.CrossRefGoogle ScholarPubMed
Uryu, Outa, Ameku, Tomotsune, Niwa, Ryusuke et al. (2015) Recent progress in understanding the role of ecdysteroids in adult insects: germline development and circadian clock in the fruit fly Drosophila melanogaster. Zoological Letters 1, 32.10.1186/s40851-015-0031-2CrossRefGoogle ScholarPubMed
Van Cauwenberghe, Lisbeth, Vanreusel, Ann, Mees, Jan, Janssen, Colin R. et al. (2013) Microplastic pollution in deep-sea sediments. Environmental Pollution 182, 495–499.Google ScholarPubMed
Vo, H.C. and Pham, M.H. (2021) Ecotoxicological effects of microplastics on aquatic organisms: a review. Environmental Science and Pollution Research International 28, 44716–44725.CrossRefGoogle ScholarPubMed
Wright, Stephanie L., Rowe, Darren, Thompson, Richard C., Galloway, Tamara S. et al. (2013) Microplastic ingestion decreases energy reserves in marine worms. Current Biology Cb 23, R1031–R1033.CrossRefGoogle ScholarPubMed
Wright, S.L., Ulke, J., Font, A., Chan, K.L.A., Kelly, F.J. et al. (2020) Atmospheric microplastic deposition in an urban environment and an evaluation of transport. Environment International 136, 105411.CrossRefGoogle Scholar