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Simultaneous Genetic Analysis of Longitudinal Means and Covariance Structure Using the Simplex Model: Application to Repeatedly Measured Weight in a Sample of 164 Female Twins

Published online by Cambridge University Press:  01 August 2014

S. Fischbein ,
P.C.M. Molenaar  and
D.I. Boomsma
S. Fischbein*
Affiliation:
Department of Educational Research, Institute of Education, Stockholm, Sweden
P.C.M. Molenaar
Affiliation:
Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands
D.I. Boomsma
Affiliation:
Department of Psychology, Free University, Amsterdam, The Netherlands
*
Department of Educational Research, Institute of Education, Box 34103, S-100 26 Stockholm, Sweden

Abstract

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The simultaneous analysis of means and covariance structures is applied to longitudinal twin data. Body weight was measured on six occasions in a sample of young female MZ and DZ twins. When average body weight at the first measurement occasion, as well as the increments in weight at later occasions, are specified in the genetic part of the model that also adequately explains the covariance structure, a good fit is obtained. In this application the increase in body weight at each occasion is weighted by the square root of the genetic variance innovation terms that represent the new genetic variance entering into the process.

Keywords

Body weightLongitudinal analysisMeansTwin data

Information

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 39 , Issue 2 , April 1990 , pp. 165 - 172
Copyright
Copyright © The International Society for Twin Studies 1990

References

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